Linardopoulos, Dr Spiros spiros.linardopoulos**[ta]**.ac.uk

Exploratory & preclinical development and CRUKD/15/005 A Phase I frst in human trial of CCT241736 an orally bioavailable dual FLT3-Aurora Kinase inhibitor to treat patients with FLT3-mutated Acute Myeloid Leukaemia (AML) Institute of Cancer Research 01/08/2012 30/06/2019 New Agents Committee - DD Project Proposal New Agents Committee

Linch, Professor David CRUK/12/017: Long term follow-up of "An Intergroup Randomised Trial of Rituximab versus Watch and Wait Strategy in Patients with Advanced Stage, Asymptomatic, Non-Bulky Follicular Lymphoma" University College London 01/02/2013 31/01/2019 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Linton, Dr Kim kim.linton**[ta]**chester.ac.uk

CRUK/12/019: ReBeL study: a randomized phase I/ II trial of lenalidomide and rituximab with or without bendamustine in patients 18 years or older with relapsed follicular lymphoma.A HOVON/GLSG study.University College London 01/11/2012 31/10/2015 Clinical Trials Awards & Advisory Committee - Feasibility Study Clinical Trials Awards & Advisory CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Lloyd, Professor Alison alison.lloyd**[ta]**.ac.uk

Identifcation of novel therapeutic targets in biogenic and regenerative pathways University College London 01/10/2014 30/09/2019 Science Committee - Programme Award Science Committee

Lockley, Dr Michelle m.lockley**[ta]**l.ac.uk

Inflammatory Cytokines and Oncolytic Adenoviruses in Ovarian Cancer Queen Mary, University of London 01/07/2011 29/02/2016 Clinical Careers Committee - Clinician Scientist Fellowship Clinical Careers Committee

Lord, Dr Christopher chris.lord**[ta]**.ac.uk

Cancer susceptibility genes Institute of Cancer Research 01/10/2012 30/09/2017 Science Committee - Programme Award Science Committee

Lorigan, Dr Paul paul.lorigan**[ta]**istie.nhs.uk

CRUK/12/020: A Phase II Trial of PLX3397 in KIT Mutant Acral and Mucosal Melanoma University of Manchester 01/09/2015 31/08/2019 Clinical Trials Awards & Advisory Committee - Feasibility Study Clinical Trials Awards & Advisory Committee

Louie, Dr Karly k.louie**[ta]**l.ac.uk

Epidemiology of oral HPV infection, impact of vaccination and surveillance in young people Queen Mary, University of London 01/01/2013 31/12/2015 Population Research Committee - Postdoctoral Fellowship Population Research Committee

Lu, Professor Xin Investigating ASPP2/Notch/p53/p63 interplay in oesophageal cancer development and prognosis University of Oxford 01/12/2014 30/11/2017 Scientifc Executive Board - CRUK/ CICAMS Project Grants Scientifc Executive Board

Lubbers, Ms Eveline TobaccoTactics.org.Monitoring tobacco industry activity to support health advocacy - developing a wiki as a new model of knowledge exchange.University of Bath 01/09/2013 29/02/2016 Tobacco Advisory Group - Project Award Tobacco Advisory Group

Luscombe, Dr Nicholas Computational Biology Group The Francis Crick Institute 01/04/2012 31/03/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Lyratzopoulos, Dr Georgios y.lyratzopoulos**[ta]**.ac.uk

Developing a stratifed approach to earlier diagnosis of cancer University College London 01/03/2015 28/02/2019 Clinical Careers Committee - Clinician Scientist Fellowship Clinical Careers Committee

What is driving general practice variation in ‘two-week wait’ referrals and use of endoscopy and imaging investigations, and does it matter for cancer outcomes? University of Cambridge 01/08/2014 31/01/2016 National Awareness and Early Diagnosis Initiative - Project Award National Awareness and Early Diagnosis Initiative

Macdonald, Dr Sara smd26h**[ta]**nmed.gla.ac.uk

An exploration of the media representation of cancer and its impact on older adults’ understanding of cancer risk and help-seeking behaviour University of Glasgow 01/01/2015 30/04/2016 Early Diagnosis Advisory Group - Project Award Early Diagnosis Advisory Group Machesky, Professor Laura l.machesky**[ta]**tson.gla.ac.uk

Actin Dynamics in Cancer Invasion and Metastasis Cancer Research UK Beatson Institute 01/06/2012 31/05/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Mackay, Professor Simon simon.mackay**[ta]**ath.ac.uk

First-in-class selective IKKalpha inhibitors for evaluation in pancreatic cancer University of Strathclyde 01/09/2014 31/10/2016 Drug Discovery Committee - Drug Discovery Project Award Drug Discovery Committee

MacKintosh, Mrs Anne a.m.mackintosh**[ta]**r.ac.uk

Cancer Research UK Centre for Tobacco Control Research (CTCR) University of Stirling 01/10/2012 30/09/2015 Tobacco Advisory Group - Programme Award Tobacco Advisory Group

Maddocks, Dr Oliver o.maddocks**[ta]**tson.gla.ac.uk

Targeting Tumour Metabolism for Cancer Therapy and Diagnosis University of Glasgow 01/09/2015 31/08/2021 New Investigator Committee - Career Development Fellowship New Investigator CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Maher, Dr John john.maher**[ta]**.ac.uk

Development of gamma delta (gd) T-cell immunotherapy for triple negative breast cancer (TNBC) King's College London 01/02/2015 31/01/2017 Drug Discovery Committee - CRUK & BHC Drug Discovery Project Award Drug Discovery Committee

Malanchi, Dr Ilaria Tumour Host Interaction Laboratory The Francis Crick Institute 01/06/2011 31/05/2018 Biological Sciences Committee - Institute Group Award Science Committee

Marais, Professor Richard richard.marais**[ta]**k.manchester.ac.uk

CRUK Manchester Institute Drug Discovery Programme Cancer Research UK Manchester Institute 01/04/2014 31/03/2019 Drug Discovery Committee - Small Molecule Programme Award Drug Discovery Committee

Cancer Research UK Manchester Institute Core Grant University of Manchester 01/04/2015 31/03/2020 Scientifc Executive Board - Institute Grant Funded Core Award Scientifc Executive Board

Molecular Oncology Group University of Manchester 01/05/2012 30/04/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Lung Cancer Centre of Excellence Award University of Manchester 01/01/2015 31/03/2016 Scientifc Executive Board - Lung Cancer Centre of Excellence Scientifc Executive Board

Markowetz, Dr Florian florian.markowetz**[ta]**k.cam.ac.uk

Computational Biology Laboratory University of Cambridge 01/03/2014 28/02/2019 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Marsden, Professor Paul paul.marsden**[ta]**.ac.uk

NCRI: PET Core Lab King's College London 01/08/2012 31/03/2017 Scientifc Executive Board - Initiative Award Scientifc Executive Board

Marshall, Professor Chris chris.marshall**[ta]**.ac.uk

GTPase Signalling in Cancer Institute of Cancer Research 01/10/2013 30/09/2016 Science Committee - Programme Award Science Committee

Marshall, Professor John j.f.marshall**[ta]**l.ac.uk

Preclinical development & CRUKD/17/002 a First-inMan Phase I trial of 264RAD, a therapeutic antibody targeting of integrin alphavß6 in Pancreatic Ductal Adenocarcinoma Queen Mary, University of London 01/11/2013 31/08/2019 New Agents Committee - DD Project Proposal New Agents Committee

Marshall, Professor Tom t.p.marshall**[ta]**m.ac.uk

ColoRectal Early Diagnosis: Information Based Local Evaluation (CREDIBLE) University of Birmingham 01/07/2011 31/12/2015 National Awareness and Early Diagnosis Initiative - Project Award National Awareness and Early Diagnosis Initiative

Martin, Professor Paul paul.martin**[ta]**stol.ac.uk

Live imaging and genetic analysis of the host response to early stages of cancer initiation in zebrafsh embryos and larvae University of Bristol 01/10/2013 30/09/2018 Science Committee - Programme Award Science Committee

Martin, Professor Richard richard.martin**[ta]**stol.ac.uk

Reducing the burden of cancer: causal risk factors, mechanistic targets and predictive biomarkers University of Bristol 01/06/2015 31/05/2020 Population Research Committee - Programme Award Population Research Committee

Evaluating population-based screening for localised prostate cancer in the United Kingdom: the CAP (Comparison Arm for ProtecT) randomised controlled trial University of Bristol 01/01/2013 31/12/2016 Population Research Committee - Project Award Population Research CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Mason, Dr Jody j.mason**[ta]**h.ac.uk

Iterative Design, Randomisation, Selection, Truncation and Characterisation to Generate Small High Afnity Antagonists of the Activator Protein-1 Motif University of Bath 01/09/2010 31/08/2016 Biological Sciences Committee - Career Establishment Award Science Committee

Matakidou, Dr Athena athena.matakidou**[ta]**k.cam.ac.uk

Generation of mouse models of renal cell carcinoma by forward genetics University of Cambridge 01/08/2010 31/07/2016 Clinical Careers Committee - Clinician Scientist Fellowship Clinical Careers Committee

Maughan, Professor Timothy tim.maughan**[ta]**ology.ox.ac.uk

RHYTHM-2: modulation of Radiotherapy according to HYpoxia: exploiting changes in the Tumour Microenvironment to improve outcome in rectal cancer using PF-05212384.University of Oxford 01/05/2014 31/10/2015 New Agents Committee - PreClinical Grants New Agents Committee

Maxwell, Dr Ross Pharmacological Imaging in Cancer Newcastle University 01/12/2008 31/03/2016 Clinical and Translational Research Committee - Programme Award Science Committee

Mazhar, Dr Danish danish.mazhar**[ta]**enbrookes.nhs.uk

CRUK/14/045 P3BEP Trial Phase 3 Accelerated BEP Trial: A randomised phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours Cambridge University Hospitals NHS Trust 01/06/2015 31/05/2021 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

McCarthy, Dr Helen h.mccarthy**[ta]**.ac.uk

Development of the RALA-hOC/iNOS gene therapy for metastatic breast and prostate cancer Queen's University Belfast 01/08/2014 31/07/2016 Drug Discovery Committee - Drug Discovery Project Award Drug Discovery Committee

McDonald, Professor Neil neil.mcdonald**[ta]**ck.ac.uk

Structural biology of signalling assemblies at the cell membrane The Francis Crick Institute 01/12/2014 30/11/2019 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

McKenna, Professor Gillies CRUK & EPSRC Cancer Imaging Centre in Oxford University of Oxford 01/12/2013 30/11/2018 Scientifc Executive Board - Cancer Imaging Centres Scientifc Executive Board

Cancer Research UK/MRC Oxford Institute for Radiation Oncology Core Grant University of Oxford 01/04/2012 31/03/2017 Scientifc Executive Board - Institute Grant Funded Core Award Scientifc Executive Board

Oxford CRUK Major Centre University of Oxford 01/05/2015 30/04/2017 Scientifc Executive Board - Major Centres Award Scientifc Executive Board

McMillan, Dr Andrew andrew.mcmillan**[ta]**.nhs.uk

CRUKE/11/060: Comparison of Inotuzumab Ozogamicin (IO) in combination with Rituximab, Cyclophosphamide, Vincristine and Prednisolone (R-CVP) versus R-Gemcitabine-CVP or R-CEOP in Elderly Aggressive Non Hodgkins Lymphoma assessed as unft for R-CHOP therapy, a randomised phase II clinical trial.University College London 01/03/2015 28/02/2017 Clinical Trials Awards & Advisory Committee - Endorsement - Feasibility Study Clinical Trials Awards & Advisory Committee

McNeill, Professor Ann ann.mcneill**[ta]**.ac.uk

Secondary analysis of e-cigarette survey data King's College London 01/05/2015 31/12/2016 Tobacco Advisory Group - Project Award Tobacco Advisory GroupCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.McNeish, Professor Iain iain.mcneish**[ta]**sgow.ac.uk

Preclinical combination studies with Hedgehog pathway inhibitor LY2940680 and paclitaxel in ovarian cancer University of Glasgow 01/03/2015 29/02/2016 New Agents Committee - PreClinical Grants New Agents Committee

McShane, Dr Charlene c.mcshane**[ta]**.ac.uk

Population-based register of monoclonal gammopathy of undetermined signifcance (MGUS): establishing risk prediction models and investigating patient outcomes Queen's University Belfast 01/03/2015 28/02/2018 Population Research Committee - Postdoctoral Fellowship Population Research Committee

Meads, Dr Catherine catherine.meads**[ta]**nel.ac.uk

Sexual orientation and smoking - an evaluation using the Smoking Toolkit Study Brunel University 01/04/2015 31/03/2017 Population Research Committee - Project Award Population Research Committee

Mehanna, Professor Hisham h.mehanna**[ta]**m.ac.uk

CRUK/11/043: De-ESCALaTE-HPV: Determination of Epidermal growth factor receptor-inhibitor (cetuximab) vs Standard Chemotherapy early and Late Toxicity Events in Human Papilloma Virus Positive oropharyngeal carcinoma University of Warwick 01/09/2011 31/08/2017 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

CRUK/13/026: CompARE: Phase III randomised controlled trial Comparing Alternative Regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer University of Birmingham 01/11/2014 31/10/2022 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

CRUK/11/043: Head and neck squamous cell carcinoma Tissue Collection for the De-ESCALaTE trial (De-ESCALaTE COLLECT) University of Birmingham 01/02/2014 31/01/2024 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Meier, Professor Petra p.meier**[ta]**feld.ac.uk

Adaptation of the Shefeld Alcohol Policy Model version3 to model economic impact of alcohol policies for CRUK University of Shefeld 01/09/2015 31/08/2016 Policy Research Centre for Cancer Prevention - Commissioned Research Policy Research Centre for Cancer Prevention

Melcher, Professor Alan a.a.melcher**[ta]**ds.ac.uk

Improving cancer therapy by systemic administration of oncolytic viruses University of Leeds 01/09/2011 31/08/2016 Science Committee - Programme Award Science Committee

Meyer, Professor Tim t.meyer**[ta]**.ac.uk

Preclinical development & CRUKD/16/003 a Phase I trial of DARPIN (Indium-111 radio-labelled G3 Designed Ankyrin Repeat Protein) for SPECT HER2 imaging in advanced breast cancer University College London 01/07/2013 30/09/2018 New Agents Committee - DD Project Proposal New Agents Committee

Michael, Dr Agnieszka a.michael**[ta]**rey.ac.uk

CRUKE/11/059: TRIOC: A Randomised Parallel Group

Double-Blind Phase II Study to Assess the Activity of TroVax® (MVA-5T4) Versus Placebo in Patients with Relapsed Asymptomatic Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer University College London 01/04/2012 31/05/2017 Clinical Trials Awards & Advisory Committee - Endorsement - Feasibility Study Clinical Trials Awards & Advisory Committee CANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.CRUKE/11/059: TRIOC trial- A randomised parallel group double-blind phase II study to assess the activity of TroVax® (MVA-5T4) versus placebo in patients with relapsed asymptomatic epithelial ovarian, fallopian tube or primary peritoneal cancer- tumour sample collection University College London 01/11/2013 30/04/2019 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Middleton, Professor Mark Clinical Trial Research Fellowship University of Oxford 01/06/2015 31/05/2018 Clinical Trials Awards & Advisory Committee - Clinical Trial Fellowship Clinical Trials Awards & Advisory Committee

CRUKE/11/033: The PACMEL study: Randomised phase 2 study of paclitaxel with or without GSK1120212 in advanced wt BRAF melanoma University of Oxford 01/06/2013 30/11/2015 Clinical Trials Awards & Advisory Committee - Endorsement - Feasibility Study Clinical Trials Awards & Advisory Committee

CRUK/10/008: ANZMTG-WBRT: Whole brain radiotherapy following local treatment on intracranial metastases of melanoma - a randomised phase III trial.University of Oxford 01/07/2010 30/06/2016 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Miller, Dr Crispin crispin.miller**[ta]**k.manchester.ac.uk

The regulatory role of the non coding genome in cancer Cancer Research UK Manchester Institute 01/07/2012 30/06/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Miller, Dr Martin QQR Cancer Research UK Cambridge Institute 01/01/2015 31/12/2020 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Mishima, Dr Masanori Characterisation of cytokinesis proteins, their regulation and cooperativity using biophysical and cell biological approaches University of Warwick 01/10/2010 30/09/2016 Science Committee - Programme Award Science Committee

Mole, Dr David drmole**[ta]**l.ox.ac.uk

Target discovery in renal cell carcinoma: hypoxia and epigenetic pathways University of Oxford 01/05/2013 30/04/2018 Science Committee - Programme Award Science Committee

Moodie, Dr Crawford c.s.moodie**[ta]**r.ac.uk

Young adult's perceptions of cigarette design University of Stirling 01/09/2015 29/02/2016 Tobacco Advisory Group - Commissioned Research Tobacco Advisory Group

Adult Tobacco Policy Survey University of Stirling 01/11/2014 30/11/2016 Tobacco Advisory Group - Project Award Tobacco Advisory Group

Moores, Dr Carolyn c.moores**[ta]**l.cryst.bbk.ac.uk

Mechanism of action and inhibition of kinesin-8 mitotic motors Birkbeck College 01/05/2012 31/12/2015 Biological Sciences Committee - Project Award Science Committee

Morris, Dr Edward edward.morris**[ta]**.ac.uk

Structural biology of key components of the ubiquitin/ proteasome pathway Institute of Cancer Research 01/12/2013 30/11/2018 Science Committee - Programme Award Science Committee