Morris, Dr Joanna j.morris.3**[ta]**m.ac.uk

Ubiquitin processing in cancer development and treatment University of Birmingham 01/01/2015 31/12/2019 Science Committee - Programme Award Science Committee

Morrison, Dr David Outcome of cancer patients with critical illness admitted to Intensive Care University of Glasgow 01/07/2013 31/10/2015 Population Research Committee - Project Award Population Research CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Morton, Professor Dion dion.morton**[ta]**.nhs.uk

CRUK/07/014: FOxTROT: Fluoropyrimidine, Oxaliplatin and Targated Receptor pre-Operative Therapy: a controlled trial in high-risk operable colon cancer (supported by the Bobby Moore fund.) University of Birmingham 01/07/2007 31/03/2018 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Mueschen, Professor Markus markus.muschen**[ta]**f.edu Harnessing negative pre-B cell selection to overcome drug-resistance in pre-B acute lymphoblastic leukaemia University of Cambridge 01/07/2014 30/06/2019 Science Committee - Programme Award Science Committee

Mukherjee, Dr Somnath somnath.mukherjee**[ta]**ology.ox.ac.uk

CRUK/07/040: SCALOP 2 University of Oxford 01/05/2014 31/08/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Murchie, Dr Peter p.murchie**[ta]**n.ac.uk

Does place of residence, distance and travelling times from health services within Northeast Scotland influence the diagnostic pathway and outcomes from eight common cancers: analysis of a linked dataset University of Aberdeen 01/09/2014 31/08/2016 National Awareness and Early Diagnosis Initiative - Project Award National Awareness and Early Diagnosis Initiative

Mussai, Dr Francis francis.mussai**[ta]**.nhs.uk

Understanding and targeting the immunosuppressive microenvironment in neuroblastoma University of Birmingham 01/03/2015 28/02/2019 Clinical Careers Committee - Clinician Scientist Fellowship Clinical Careers Committee

Narita, Dr Masashi Cellular senescence and tumour suppressors Cancer Research UK Cambridge Institute 01/10/2011 30/09/2016 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Nasmyth, Professor Kim kim.nasmyth**[ta]**ch.ox.ac.uk

Establishment of sister chromatid cohesion by cohesin University of Oxford 01/04/2011 31/03/2016 Science Committee - Programme Award Science Committee

Nathan, Dr Paul CRUKE/13/033: SELPAC: A Randomised 3-arm Phase II study of continuous Selumetinib versus continuous or interrupted Selumetinib in combination with weekly Paclitaxol in Advanced Uveal Melanoma (AZ/NCRN) University of Liverpool 01/03/2015 28/02/2017 Clinical Trials Awards & Advisory Committee - Endorsement - Feasibility Study Clinical Trials Awards & Advisory Committee

Näthke, Professor Inke inke**[ta]**esci.dundee.ac.uk

The adenomatous polyposis protein in colorectal cancer: from biochemistry to tissue architecture University of Dundee 01/10/2009 30/09/2015 Science Committee - Programme Award Science Committee

Neil, Professor James James.Neil**[ta]**sgow.ac.uk

New approaches to modelling human leukaemia University of Glasgow 01/01/2011 31/12/2015 Science Committee - Programme Award Science Committee

Neoptolemos, Professor John Cancer Research UK Liverpool Cancer Trials Unit University of Liverpool 01/10/2013 30/09/2018 Clinical and Translational Research Committee - Clinical Trials Unit - Programme Award Clinical Trials Awards & Advisory Committee

CRUK/07/024: ESPAC4: EUROPEAN STUDY GROUP FOR PANCREATIC CANCER (ESPAC) -Trial 4.Combination versus single agent adjuvant chemotherapy in resectable pancreatic cancer.University of Liverpool 01/12/2007 30/11/2015 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Ng, Professor Tony CRUK & EPSRC Cancer Imaging Centre at KCL & UCL King's College London 01/12/2013 30/11/2018 Scientifc Executive Board - Cancer Imaging Centres Scientifc Executive Board

Nicholson, Dr James CRUK/10/038: SIOP CNS GCT II: Prospective Trial for the diagnosis and treatment of children, adolescents and young adults with Intracranial Germ Cell Tumours University of Birmingham 01/04/2012 31/03/2019 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Nicholson, Dr Steve CRUK/13/005: InPACT - International Penile Advanced Cancer Trial (International Rare Cancers Initiative study - IRCI 004) (supported by Stand Up To Cancer) Institute of Cancer Research 01/06/2015 31/05/2023 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Norman, Professor Jim j.norman**[ta]**tson.gla.ac.uk

Integrin trafcking in invasion and metastasis Cancer Research UK Beatson Institute 01/03/2014 28/02/2019 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Nurse, Professor Paul paul.nurse**[ta]**ck.ac.uk

Cancer Research UK Francis Crick Institute Core Grant The Francis Crick Institute 01/04/2015 31/03/2021 Scientifc Executive Board - Institute Grant Funded Core Award Scientifc Executive Board

Cell Cycle Laboratory The Francis Crick Institute 01/10/2012 30/09/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Nutting, Professor Christopher chris.nutting**[ta]**.nhs.uk

CRUK/14/014: DARS - a phase III randomised multicentre trial of dysphagia optimized intensity modulated radiotherapy versus standard intensity modulated radiotherapy in head and neck cancer Institute of Cancer Research 01/06/2015 31/01/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

O'Brien, Professor Stephen stephen.o'brien**[ta]**castle.ac.uk

CRUKE/09/003: SPIRIT 2: a phase III, prospective randomised comparison of imatinib 400mg daily versus dasatinib 100mg daily in patients with newlydiagnosed chronic phase chronic myeloid leukaemia Newcastle University 01/04/2009 31/05/2018 Clinical Trials Awards & Advisory Committee - Endorsement - Late Phase Study Clinical Trials Awards & Advisory Committee

O'Connor, Dr James james.o'connor**[ta]**chester.ac.uk

MRI measurement of tumour spatial heterogeneity: pharmacological biomarker discovery and assay development University of Manchester 01/01/2013 31/12/2016 Clinical Careers Committee - Clinician Scientist Fellowship Clinical Careers Committee

Odom, Dr Duncan Regulatory Circuitry Laboratory Cancer Research UK Cambridge Institute 01/12/2010 30/11/2015 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

O'Driscoll, Professor Mark m.o-driscoll**[ta]**sex.ac.uk

Understanding the wider biological impacts of impaired ATR-ATM DNA damage response pathway function upon signal transduction, cell cycle checkpoint control and DNA repair University of Sussex 01/07/2013 30/06/2018 Science Committee - Programme Award Science Committee

Oelfke, Professor Uwe uwe.oelfke**[ta]**.ac.uk

Optimisation of management in clinical oncology Institute of Cancer Research 01/10/2009 30/09/2015 Science Committee - Programme Award Science Committee

Advances in Physics for Precision Radiotherapy Institute of Cancer Research 01/01/2015 31/12/2019 Science Committee - Programme Award Science CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Olson, Professor Michael m.olson**[ta]**tson.gla.ac.uk

The role of the actin-myosin cytoskeleton in tissue homeostasis and cancer.Cancer Research UK Beatson Institute 01/03/2014 28/02/2019 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

O'Neill, Dr Eric eric.oneill**[ta]**ology.ox.ac.uk

Signalling Group University of Oxford 01/11/2013 31/10/2018 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

O'Rorke, Dr Michael m.ororke**[ta]**.ac.uk

Beta adrenergic receptor expression and beta-blocker use: association with breast cancer survival and prognosis Queen's University Belfast 01/02/2014 31/01/2017 Population Research Committee - Postdoctoral Fellowship Population Research Committee

Ottensmeier, Professor Christian CRUKE/10/019: ICE: A Phase II trial of the addition of Ipilimumab to Carboplatin and Etoposide chemotherapy for the frst line treatment of extensive stage small cell lung cancer University of Southampton 01/12/2010 31/12/2015 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Exploratory & preclinical development & CRUKD/17/003 a Phase I frst in human trial of ASTVAC2.Telomerase pulsed allogeneic Dendritic Cells for the immunotherapy of lung cancer (NSCLC) University of Southampton 01/04/2014 31/03/2018 New Agents Committee - DD Project Proposal New Agents Committee

CRUKD/15/004 A Cancer Research UK randomised double blind placebo controlled Phase IIa trial of p110delta PI3-kinase inhibitor AMG319 given orally as neoadjuvant therapy in patients with HPV negative head and neck squamous cell carcinoma (HNSCC).University of Southampton 01/06/2014 31/10/2018 New Agents Committee - DD Project Proposal New Agents Committee

Improving Immunotherapy: Understanding and Predicting Protective Immune Responses in Cancer University of Southampton 01/02/2013 31/01/2016 Science Committee - Programme Award Science Committee

Palmer, Professor Daniel daniel.palmer**[ta]**erpool.ac.uk

CRUK/14/012: CALGB80802 - Phase III randomised study of Sorafenib plus Doxorubicin versus Sorafenib in patients with Advanced Hepatocelluar Carcinoma (HCC) University of Liverpool 01/06/2015 30/11/2017 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Palmieri, Professor Carlo c.palmieri**[ta]**erpool.ac.uk

CRUK/11/025: IRIS: A Phase II study to assess the safety and efcacy of the steroid sulfatase inhibitor Irosustat in combination with aromatase inhibition in ER positive locally advanced or metastatic breast cancer patients.Imperial College London 01/05/2012 31/05/2016 Clinical Trials Awards & Advisory Committee - Feasibility Study Clinical Trials Awards & Advisory Committee

Paraskeva, Professor Chris c.paraskeva**[ta]**stol.ac.uk

Colorectal tumour cell survival mechanisms and chemoprevention University of Bristol 01/01/2011 30/06/2016 Science Committee - Programme Award Science Committee

Parker, Dr Chris CRUK/07/008: RADICALS: Randomised phase III trial of adjuvant vs selective salvage treatment after radical prostatectomy for localised prostate cancer University College London 01/04/2007 31/03/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Parker, Professor Peter The transformation-associated actions, the signalling network lessons and the intervention opportunities for the PKC superfamily.The Francis Crick Institute 01/11/2012 31/10/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Partridge, Dr Mike Radiotherapy Physics Reseach Group Cancer Research UK/ MRC Oxford Institute for Radiation Oncology 01/03/2012 28/02/2017 Scientifc Executive Board - Institute Group Award Scientifc Executive Board

Patel, Dr Ketan Genetic insight into ethanol and reactive aldehyde induced DNA damage and epithelial cancer development Medical Research Council Centre - Cambridge 01/06/2012 31/05/2017 Science Committee - Programme Award Science Commit***

Paul, Mr James James.Paul**[ta]**sgow.ac.uk

transSCOT - sample collection for translational studies in colorectal cancer University of Glasgow 01/01/2012 31/03/2016 Clinical Trials Awards & Advisory Committee - Sample Collection Clinical Trials Awards & Advisory Committee

Payne, Dr Geoffrey gsp**[ta]**.ac.uk

Evaluation of Lactate as a Biomarker in Clinical Trials of new mechanism-based anti-cancer drugs using 1H Magnetic Resonance Spectroscopy Institute of Cancer Research 01/11/2011 31/10/2015 Science Committee - Biomarker Project Award Science Committee

Pearce, Dr Mark mark.pearce**[ta]**.ac.uk

Long-term cancer risks in relation to radiation exposures received due to CT scanning in children and young adults - an extension to the existing UK cohort Newcastle University 01/04/2013 31/03/2017 Population Research Committee - Project Award Population Research Committee

Pearl, Professor Laurence laurence.pearl**[ta]**sex.ac.uk

Structural Biology of DNA Damage Response and Repair Mechanisms and its Exploitation for Drug Discovery University of Sussex 01/10/2012 30/09/2017 Science Committee - Programme Award Science Committee

Perkins, Professor Neil neil.perkins**[ta]**.ac.uk

New roles for the RelA(p65) NF-kB subunit in cancer Newcastle University 01/06/2011 31/05/2016 Science Committee - Programme Award Science Committee

Petersen, Dr Janni TOR signalling and control of mitotic commitment University of Manchester 01/12/2009 30/11/2015 New Investigator Committee - Senior Cancer Research Fellowship New Investigator Committee

Peto, Professor Sir Richard Clinical Trial Service Unit & Epidemiological Studies Unit University of Oxford 01/04/2014 31/03/2019 Population Research Committee - Programme Award Population Research Committee

Pettitt, Professor Andrew a.r.pettitt**[ta]**erpool.ac.uk

CRUKE/09/035: Randomised phase II trial of alemtuzumab, dexamethasone and lenalidomide induction followed by lenalidomide maintenance versus no further treatment for high-risk CLL.University of Liverpool 01/01/2010 31/12/2017 Clinical Trials Awards & Advisory Committee - Endorsement - Late Phase Study Clinical Trials Awards & Advisory Committee

CRUKE/10/052: RIAltO: A Randomised Investigation of Alternative Ofatumumab-based regimens for less ft patients with CLL University of Liverpool 01/08/2011 31/07/2019 Clinical Trials Awards & Advisory Committee - Endorsement - Late Phase Study Clinical Trials Awards & Advisory CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.CRUK/08/024: PACIFICO (previously RiCh FLO): Purine-Alkylator Combination In Follicular lymphoma Immuno-Chemotherapy for Older patients University of Liverpool 01/11/2008 31/10/2016 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Serial measurement of the subclinical leukaemic burden as an early biomarker for overt relapse in chronic lymphocytic leukaemia University of Liverpool 01/03/2014 30/09/2018 Science Committee - Biomarker Project Award Science Committee

Pharoah, Professor Paul pp10001**[ta]**schl.cam.ac.uk

The genetic and molecular epidemiology of breast and ovarian cancer University of Cambridge 01/10/2013 30/09/2018 Science Committee - Programme Award Science Committee

Phillips, Professor David david.h.phillips**[ta]**.ac.uk

Human biomonitoring and carcinogen activation King's College London 01/10/2012 30/09/2017 Science Committee - Programme Award Science Committee

Picton, Dr Susan susan.picton**[ta]**.net CRUK/13/011: Phase I-II study of Vinblastine in combination with Nilotinib in children, adolescents and young adults with refractory or recurrent low grade glioma: An ITCC and SIOPE-Brain tumour protocol (jointly funded by The Brain Tumour Charity and supported by Stand Up To Cancer) University of Birmingham 01/11/2014 31/10/2020 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee

Piddini, Dr Eugenia e.piddini**[ta]**don.cam.ac.uk

Competitive cell interactions in normal physiology and cancer University of Cambridge 01/02/2011 31/07/2016 Science Committee - Programme Award Science Committee

Pillay, Dr Nischalan nischalan.pillay.09**[ta]**.ac.uk

Using genomics to identify new therapeutic avenues for patients with unclassifable sarcomas.University College London 01/01/2015 31/12/2018 Clinical Careers Committee - Clinician Scientist Fellowship Clinical Careers Committee

Pines, Professor Jonathon How is mitosis controlled by ubiquitin-mediated proteolysis? University of Cambridge 01/10/2012 30/09/2017 Science Committee - Programme Award Science Committee

Plummer, Professor Elizabeth Ruth.Plummer**[ta]**castle.ac.uk

CRUKD/08/042 A CR UK Phase II trial of PARP inhibitor AG014699 in metastatic breast & ovarian cancer with known BRCA1 or BRCA2 mutation Newcastle University 01/10/2005 30/09/2015 New Agents Committee - DD Project Proposal New Agents Committee

CRUKD/12/004: A phase I pharmacokinetic and pharmacodynamic frst in class study of AZD3965, a potent Monocarboxylate Transporter 1 inhibitor (MCT1) in advanced cancer including prostate cancer & NHL expressing MCT1.Newcastle University 01/09/2010 30/09/2018 New Agents Committee - DD Project Proposal New Agents Committee

Pollard, Dr Steven steven.pollard**[ta]**ac.uk

The role of SOX and FOX genes in orchestrating transcriptional and epigenetic programs in glioblastoma University of Edinburgh 01/07/2014 30/06/2020 New Investigator Committee - Senior Cancer Research Fellowship New Investigator Committee

The role of SOX and FOX genes in orchestrating transcriptional and epigenetic programs in glioblastoma University of Edinburgh 01/07/2014 30/06/2018 New Investigator Committee - Studentship New Investigator CommitteeCANCER RESEARCH UK our Funded research Principal Investigator email address Project Title host Institution start date end date Funding scheme Funding Commit***

The above is a list of Cancer Research UK’s active publishable awards as of 30 September 2015.For any further enquiries please contact researcher.comments**[ta]**cer.org.uk.Ponder, Professor Sir Bruce bruce.ponder**[ta]**k.cam.ac.uk

Gene expression patterns as a readout of polygenic susceptibility; potential applications to risk estimation and to prevention in lung cancer University of Cambridge 01/04/2013 31/03/2016 Scientifc Executive Board - Programme Award Scientifc Executive Board

Popat, Dr Sanjay sanjay.popat**[ta]**.nhs.uk

CRUKE/10/040: TIMELY: Trial of BIBW2992 In suspected Mutant EGFR Lung Cancer patients unft for chemotherapY or poor performance status University College London 01/11/2011 29/02/2016 Clinical Trials Awards & Advisory Committee - Endorsement - Feasibility Study Clinical Trials Awards & Advisory Committee

Powell, Dr Melanie melanie.powell**[ta]**tshealth.nhs.uk

CRUK/10/002: DEPICT - Dose Escalation Pelvic IMRT in Cervical Tumours (A Phase I/II dose escalation study of simultaneous integrated boost intensity-modulated radiotherapy for locally advanced cervical cancer) Barts and The London NHS Trust 01/04/2010 31/03/2016 Clinical Trials Awards & Advisory Committee - Feasibility Study Clinical Trials Awards & Advisory Committee

CRUK/08/001: PORTEC-3: Randomised Phase III Trial Comparing Concurrent Chemoradiation and Adjuvant Chemotherapy with Pelvic Radiation Alone in High Risk and Advanced Stage Endometrial Carcinoma.University College London 01/01/2008 31/12/2018 Clinical Trials Awards & Advisory Committee - Late Phase Study Clinical Trials Awards & Advisory Committee